Lloyd Catherine May c.lloyd@auckland.ac.nz The University of Auckland The Bioengineering Institute 2002-06-17 Added more metadata. Lloyd Catherine May 2002-07-22 The University of Auckland, Bioengineering Institute A Generic Model Of Odd-Chain Fatty Acid Oxidation Below is a CellML description of a general model of odd-chain fatty acid oxidation. It is not based on a specific published mathematical model, but instead it is based on a textbook defined pathway. The general sequential structure and all the reactant, product and enzyme components are included. Michaelis-Menten enzyme kinetics are assumed. The purpose of this description is to illustrate how CellML can be used to model a general metabolic pathway. Catherine Lloyd Homo sapiens keyword metabolism Bronk J Ramsey Human Metabolism 1999 Addison Wesley Longman Limited location England $\frac{d \mathrm{Propionyl\_CoA}}{d \mathrm{time}}=\mathrm{delta\_Propionyl\_CoA\_rxn0}$ $\frac{d \mathrm{Methylmalonyl\_CoA}}{d \mathrm{time}}=\mathrm{delta\_Methylmalonyl\_CoA\_rxn0}+\mathrm{delta\_Methylmalonyl\_CoA\_rxn1}$ $\frac{d \mathrm{Methylmalonyl\_B12}}{d \mathrm{time}}=\mathrm{delta\_Methylmalonyl\_B12\_rxn1}+\mathrm{delta\_Methylmalonyl\_B12\_rxn2}$ $\frac{d \mathrm{Succinyl\_CoA}}{d \mathrm{time}}=\mathrm{delta\_Succinyl\_CoA\_rxn3}$ $\frac{d \mathrm{ATP}}{d \mathrm{time}}=\mathrm{delta\_ATP\_rxn0}$ $\frac{d \mathrm{ADP}}{d \mathrm{time}}=\mathrm{delta\_ADP\_rxn0}$ $\frac{d \mathrm{Pi}}{d \mathrm{time}}=\mathrm{delta\_Pi\_rxn0}$ $\frac{d \mathrm{CO2}}{d \mathrm{time}}=\mathrm{delta\_CO2\_rxn0}$ $\frac{d \mathrm{Deoxyadenosyl\_5\_B12}}{d \mathrm{time}}=\mathrm{delta\_Deoxyadenosyl\_5\_B12\_rxn3}+\mathrm{delta\_Deoxyadenosyl\_5\_B12\_rxn1}$ $\frac{d \mathrm{Succinyl\_B12}}{d \mathrm{time}}=\mathrm{delta\_Succinyl\_B12\_rxn2}+\mathrm{delta\_Succinyl\_B12\_rxn3}$ $\frac{d \mathrm{Deoxyadenosine\_5}}{d \mathrm{time}}=\mathrm{delta\_Deoxyadenosine\_5\_rxn1}+\mathrm{delta\_Deoxyadenosine\_5\_rxn3}$ $\mathrm{rate}=\frac{\mathrm{vmax0}\mathrm{Propionyl\_CoA}\mathrm{ATP}\mathrm{CO2}}{\mathrm{km0}+\mathrm{Propionyl\_CoA}+\mathrm{ATP}+\mathrm{CO2}}$