Lloyd Catherine May c.lloyd@auckland.ac.nz The University of Auckland The Bioengineering Institute 2002-03-05 The University of Auckland, Bioengineering Research Group A model of LDH in human erythrocytes. This is the CellML description of Mulquiney and Kuchel's mathematical model of LDH in human erythrocytes (1999). Catherine Lloyd Homo Sapiens erythrocyte keyword metabolism erythrocyte 10477269 Mulquiney Peter J Kuchel Philip W Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: equations and parameter refinement 1999-09-15 Biochemical Journal 342 581 596 E free LDH $\frac{d E}{d \mathrm{time}}=\mathrm{delta\_E\_rxn3}+\mathrm{delta\_E\_rxn0}+\mathrm{delta\_E\_rxn4}$ B Pyr $\frac{d B}{d \mathrm{time}}=\mathrm{delta\_B\_rxn1}+\mathrm{delta\_B\_rxn4}$ $\frac{d \mathrm{EB}}{d \mathrm{time}}=\mathrm{delta\_EB\_rxn4}$ A NADH $\frac{d A}{d \mathrm{time}}=\mathrm{delta\_A\_rxn0}$ $\frac{d \mathrm{EA}}{d \mathrm{time}}=\mathrm{delta\_EA\_rxn0}+\mathrm{delta\_EA\_rxn1}$ Q NAD+ $\frac{d Q}{d \mathrm{time}}=\mathrm{delta\_Q\_rxn3}$ $\frac{d \mathrm{EQ}}{d \mathrm{time}}=\mathrm{delta\_EQ\_rxn2}+\mathrm{delta\_EQ\_rxn3}$ P Lac $\frac{d P}{d \mathrm{time}}=\mathrm{delta\_P\_rxn2}$ $\frac{d \mathrm{EPQ\_EAB}}{d \mathrm{time}}=\mathrm{delta\_EPQ\_EAB\_rxn1}+\mathrm{delta\_EPQ\_EAB\_rxn2}$ $\mathrm{rate}=\mathrm{k0}EA+-(\mathrm{k0\_}\mathrm{EA})$ $\mathrm{rate}=\mathrm{k1}\mathrm{EA}B+-(\mathrm{k1\_}\mathrm{EPQ\_EAB})$ $\mathrm{rate}=\mathrm{k2}\mathrm{EPQ\_EAB}+-(\mathrm{k2\_}P\mathrm{EQ})$ $\mathrm{rate}=\mathrm{k3}\mathrm{EQ}+-(\mathrm{k3\_}QE)$ $\mathrm{rate}=\mathrm{k4}EB+-(\mathrm{k4\_}\mathrm{EB})$